MODIFIED PROTEIN GLUTAMINASE

Abstract: the purpose of the present invention is to provide a protein glutaminase having improved oxidation stability. a protein glutaminase including a polypeptide including an amino acid sequence in which at least one substitution among (a) substitution of a valine residue or an alanine residue for the position 121 amino acid residue and (b) substitution of a cysteine residue or an aspartic acid residue for the position 142 amino acid residue has been introduced in an amino acid sequence shown in seq id no: 1 improves the oxidation stability over that of a polypeptide including the amino acid sequence shown in seq id no: 1.

Inventor(s): Atsushi Ono, Kazunori Yoshida, Ryutaro Ariyoshi

CPC Classification: C12N9/80 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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