HMPV ANTIBODIES AND THEIR USE

Abstract: antibodies and antigen binding fragments that specifically bind to human metapneumovirus (hmpv) f protein and neutralize hmpv are disclosed. nucleic acids encoding these antibodies, vectors and host cells are also provided. the disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit an hmpv infection or detect a hmpv infection.

Inventor(s): Jarrod Mousa, Jiachen Huang, Avik Banerjee

CPC Classification: C07K16/10 (PEPTIDES (peptides in foodstuffs ; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs ; preparations for medicinal purposes ; peptides containing beta-lactam rings ; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, ; ergot alkaloids of the cyclic peptide type ; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids ; macromolecular products derived from proteins ; preparation of glue or gelatine ; single cell proteins, enzymes ; genetic engineering processes for obtaining peptides ; compositions for measuring or testing processes involving enzymes ; investigation or analysis of biological material ))

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