MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES

Abstract: the present disclosure relates to modular linker compounds for target-binding drug conjugates (tbdcs) and in particular to modular linker compounds for antibody-drug-conjugates (adcs). the present disclosure further relates to methods of synthesizing the modular linker compound, to target-binding drug conjugates comprising the modular linker compound of the present disclosure as well as to pharmaceutical compositions comprising target-binding drug conjugates compound of the present disclosure. embodiments of the present disclosure have been particularly developed as target-binding drug conjugates for use in the treatment of cancer and will be described hereinafter with reference to this application. however, it will be appreciated that the present disclosure is not limited to this particular field of use.

Inventor(s): Christoph Mueller, Hendrik Gruss, Torsten Hechler, Valentin Petrich

CPC Classification: A61K47/6889 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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