METHODS AND COMPOSITIONS FOR CONTROLLING T CELL ACTIVATION

Abstract: the disclosure is directed, in part, to novel drug-responsive t cell factors providing temporal and/or spatial control over t cell (e.g., car t cell) activation and/or proliferation, t cells comprising the t cell factors, nucleic acid encoding the t cell factors, and methods for using and producing the same.

Inventor(s): Marcela V. Maus, Michael Charles Kann, Max Jan

CPC Classification: A61K35/17 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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