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20250186470. Compositions Met (THE UNIVERSITY OF CHICAGO)

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Compositions and Methods Using Lactulose for Treating Disease

Abstract: in some aspects, provided herein are methods for treating a liver disease or associated condition in a subject, and related compositions. in some embodiments, the composition comprises lactulose and a commensal organism, such as a commensal bacterial species. in some embodiments, the patient has been determined to have a microbiome profile and metabolic profile in a fecal sample from the patient, which may be indicative that the patient will benefit from the treatment.

Inventor(s): Matthew A. Odenwald, ERIC G. PAMER

CPC Classification: A61K31/7016 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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