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20250186437. Carboline Compounds (PTC Therapeutics, .)

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CARBOLINE COMPOUNDS AND USE THEREOF

Abstract: provided herein are �-carboline compounds and their use to inhibit dihydroorotate dehydrogenase (dhodh):

Inventor(s): Ramil Baiazitov, Liangxian Cao, Matteo Chierchia, Bradley B. Gilbert, Woohyung Jeon, Malte Mikus, Young-Choon Moon, Zachary Powers, Hongyu Ren, Gang Wang, Jin Zhuo

CPC Classification: A61K31/506 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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