Method of Preventing and Treating Chemotherapy- Induced Alopecia

Abstract: compositions and methods for treating alopecia, particularly chemotherapy-induced alopecia, using oxidizers or oxidants, pro-oxidant compounds, or activators of p53. compositions comprising organic peroxides such as, cumene hydroperoxide, tert-butyl hydroperoxide (t-bhp), hydrogen peroxide, benzoyl peroxide are preferred. compositions may be applied subcutaneously, percutaneously, or topically. most preferably, the compositions are applied to a treatment area prior to a round of chemotherapy to prevent or reduce hair loss in the treatment area.

Inventor(s): Joaquin J. Jimenez, John P. McCook

CPC Classification: A61K31/327 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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