METHOD

Abstract: a method for generating a biological clock including a dna methylation profile which is suitable for use with at least two different sample types, the method includes: (i) providing a first set of dna methylation profiles generated from the at least two different sample types from a plurality of subjects; (ii) generating a composite dna methylation profile from the first set of dna methylation profiles, wherein the composite dna methylation profile comprises methylation sites that have a matched status in the different sample types; and (iii) using the composite dna methylation profile to generate a biological clock using reference dna methylation profiles from one of the at least two sample types.

Inventor(s): Alix ZOLLINGER, Lorane TEXARI, Sébastien HERZIG, Philipp GUT

CPC Classification: G16B20/10 (BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY)

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