METHODS FOR IDENTIFYING MODIFICATIONS OF A POLYPEPTIDE

Abstract: systems and methods for obtaining qualitative or quantitative measurements of proteoforms of polypeptides are described. the described methods include measurements of affinity reagent binding on single-molecule polypeptide arrays to distinguish between polypeptide isoforms. the described methods may provide high resolution quantitative comparisons of proteoforms with very low copy numbers.

Inventor(s): Parag MALLICK, Jarrett D. EGERTSON, Gregory KAPP

CPC Classification: G01N33/6845 ({Methods of identifying protein-protein interactions in protein mixtures})

Search for rejections for patent application number 20250180578