20250179562. Ultrasensit (California Institute of Technology)
ULTRASENSITIVE MOLECULAR DETECTION VIA HYBRIDIZATION CHAIN REACTION
Abstract: the present application relates to hybridization chain reaction (hcr). in particular, compositions and methods are presented for ultrasensitive molecular detection using hcr signal amplification. some embodiments and methods involve cooperative probe junctions, reporter-labeled probes, and nonlinear hcr signal amplification.
Inventor(s): Harry MT Choi, Chun Hao R. Chen, Mike C. Liu, Aneesh Acharya, Niles A. Pierce
CPC Classification: C12Q1/682 (Signal amplification)
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