CBLB ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE

Abstract: the present disclosure provides improved genome editing compositions and methods for editing a casitas b-lineage (cbl) lymphoma proto-oncogene b (cblb) gene. the disclosure further provides genome edited cells for the prevention, treatment, or amelioration of at least one symptom of, a cancer, an infectious disease, an autoimmune disease, an inflammatory disease, or an immunodeficiency.

Inventor(s): Jordan JARJOUR, Kyle HAVENS, Anne-Rachel KROSTAG

CPC Classification: C12N15/102 ({Mutagenizing nucleic acids})

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