METHODS AND COMPOSITIONS FOR EDITING SBDS GENE

Abstract: provided herein is a base editor system for editing the sbds gene comprising a base editor protein and a guide polynucleotide, wherein the base editor protein comprises a polynucleotide programmable dna binding domain and a cytosine deaminase domain. methods, edited cells, and compositions thereof are also described herein.

Inventor(s): Christian Brendel

CPC Classification: C12N9/80 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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