LATRUNCULIN A FOR PRODUCING PRIMITIVE STREAK CELLS

Abstract: there is described herein a method of producing primitive streak cells for differentiation to definitive endoderm from a population of human pluripotent stem cells (hpscs), the method comprising: differentiating a population of hpscs to primitive streak cells in culture medium comprising latrunculin a (lata).

Inventor(s): Maria Cristina NOSTRO, Emily Catherine MCGAUGH, Paraish Shivam MISRA

CPC Classification: C12N5/0678 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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