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20250179428. Method Inducing Different (OSAKA UNIVERSITY)

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METHOD FOR INDUCING DIFFERENTIATION OF CORNEAL EPITHELIAL CELLS FROM PLURIPOTENT STEM CELLS

Abstract: the present invention relates to a method for inducing the differentiation of corneal epithelial cells from pluripotent stem cells. more specifically, the present invention relates to a method for autonomously differentiating pluripotent stem cells, such as human ips cells, into ectodermal cell lineage in a serum-free medium without using feeder cells and inducing the differentiation of the resultant ocular surface ectodermal lineage cells into corneal epithelial cells.

Inventor(s): Kohji NISHIDA, Ryuhei HAYASHI, Yuki ISHIKAWA

CPC Classification: C12N5/0621 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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