PLASMIN-BINDING VHHS

Abstract: the invention relates to a vhh specifically binding to plasmin. the invention further relates to a compound or a pharmaceutical composition comprising the vhh and to the use thereof in the treatment, prevention or amelioration of a disease or condition characterized by a thrombotic or embolic state.

Inventor(s): Bernd Pötzsch, Nasim Shahidi Hamedani, Eva-Maria Klein, Jens Müller, Paul-Albert König, Florian Ingo Schmidt, Jan Moritz Paul Tödtmann

CPC Classification: C07K16/40 (PEPTIDES (peptides in foodstuffs ; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs ; preparations for medicinal purposes ; peptides containing beta-lactam rings ; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, ; ergot alkaloids of the cyclic peptide type ; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids ; macromolecular products derived from proteins ; preparation of glue or gelatine ; single cell proteins, enzymes ; genetic engineering processes for obtaining peptides ; compositions for measuring or testing processes involving enzymes ; investigation or analysis of biological material ))

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