20250179078. Inhibitors Nlrp3 (PTC THERAPEUTICS, .)
INHIBITORS OF NLRP3
Abstract: the present invention relates to compounds that are useful as inhibitors of nod-like receptor protein 3 (nlrp3) inflammasome pathway, processes for the preparation of said compounds, pharmaceutical compositions comprising said compounds, methods of using said compounds in the treatment of various diseases and disorders, and medicaments containing them, and their use in diseases and disorders mediated by nlrp3.
Inventor(s): Xiaoyan ZHANG, Rauful ALAM, Lauren BEJCEK, Bradley B. GILBERT, Seyedmorteza HOSSEYNI, Eduardo HUARTE, Jing LI, Yao LIU, Kyle NIEDERER, Erica N. PARKER, Meenu PILLAI, Ettore RASTELLI, Nadiya SYDORENKO, Nanjing ZHANG, Tianyi ZHENG, Matthew G. WOLL, Handoko -
CPC Classification: C07D487/04 (Ortho-condensed systems)
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- Patent Applications
- PTC THERAPEUTICS, INC.
- CPC C07D487/04
- Xiaoyan ZHANG of Belle Mead NJ US
- Rauful ALAM of Middlesex NJ US
- Lauren BEJCEK of Englewood NJ US
- Bradley B. GILBERT of Milford NJ US
- Seyedmorteza HOSSEYNI of Highland Park NJ US
- Eduardo HUARTE of Wilmington DE US
- Jing LI of Skillman NJ US
- Yao LIU of Somerville NJ US
- Kyle NIEDERER of Titusville NJ US
- Erica N. PARKER of New Brunswick NJ US
- Meenu PILLAI of Clarksburg MD US
- Ettore RASTELLI of Jersey City NJ US
- Nadiya SYDORENKO of Princeton NJ US
- Nanjing ZHANG of Princeton NJ US
- Tianyi ZHENG of Highland Park NJ US
- Matthew G. WOLL of Dunellen NJ US
- Handoko - of Newark NJ US