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20250177656. Auto Injector Variabl (Ascendis Pharma A/S)

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AUTO INJECTOR WITH VARIABLE PLUNGER FORCE

Abstract: disclosed is a method and an auto-injector for administering a medicament. the auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper; a drive module coupled to move a plunger rod between a retracted plunger rod position and an extended plunger rod position, the plunger rod being configured to move the first stopper; a resistance sensor configured to provide a resistance signal indicative of resistance against movement of the plunger rod; and a processing unit coupled to the drive module and to the resistance sensor. the processing unit being configured to: control the drive module to move the plunger rod towards the extended plunger rod position with a plunger rod speed; determine plunger rod position; receive the resistance signal; and control the drive module to adjust movement of the plunger rod if the resistance signal is indicative of resistance against movement of the plunger rod above a high resistance threshold, wherein the high resistance threshold is based on the plunger rod position.

Inventor(s): Henrik Egesborg, Steen Jensen, Martin Nørgaard Larsen, Johnny Elkjær, Bjørn Knud Andersen

CPC Classification: A61M5/31576 (DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals ; means for inserting tampons ; devices for administering food or medicines orally ; containers for collecting, storing or administering blood or medical fluids ); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery ; chemical aspects of surgical articles ); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents )})

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