Medical Injection Device With A Plasma Treated Silicone Oil Coating

Abstract: the invention relates to a medical injection device having: a barrel having an inner surface; a stopper in gliding engagement with the barrel; and a pharmaceutical composition within the medical injection device and in contact with the inner surface of the barrel, the inner surface of the barrel comprising a coating of plasma treated silicone oil in contact with the composition, wherein the plasma treatment of silicone oil reduces the number of particles present on the surface of the coating and the number of particles released into the pharmaceutical composition contained in the medical injection device as compared to silicone oil that is not plasma treated.

Inventor(s): Sebastian Janvier, Paolo Mangiagalli, Sébastien Jouffray, Cédric Foucher, Yves Enfoux

CPC Classification: A61M5/3129 (DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals ; means for inserting tampons ; devices for administering food or medicines orally ; containers for collecting, storing or administering blood or medical fluids ); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery ; chemical aspects of surgical articles ); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents )})

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