MEMBRANE SEALS AND PROJECTIONS FOR MACROENCAPSULATION DEVICES

Abstract: a macroencapsulation device includes a frame, a first membrane layer, a second membrane layer disposed on the first membrane layer, and an interior volume between the first and second membrane layers. the interior volume can encapsulate a population of cells. the frame includes a fill port extending from an exterior of the frame to an interior of the frame, with two slots formed in the frame on opposing sides of the fill port. the slots are formed on an interior portion of the frame. the first and second membrane layers are bonded together by a seal, which extends around and defines part of a perimeter of the interior volume. the seal includes two projections disposed in the two slots of the frame. a method of manufacturing includes bonding two membrane layers to form a seal defining a perimeter of an interior volume, and inserting the projections into the slots.

Inventor(s): Christopher Thanos, Megan Billings, Matthew Watson, Jason Robert Linden, Kedar Chandrashekar Chitale

CPC Classification: A61M5/14 (DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals ; means for inserting tampons ; devices for administering food or medicines orally ; containers for collecting, storing or administering blood or medical fluids ); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery ; chemical aspects of surgical articles ); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents )})

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