METHODS OF MANUFACTURING INJECTABLE MICROGEL SCAFFOLDS

Abstract: disclosed herein are methods of manufacturing injectable microgel scaffolds, including methods of producing, purifying and concentrating microgel particles therein. the microgel scaffolds of the present disclosure are useful for a wide range of applications, such as stabilizing an implanted medical device in an implant site in a subject. the microgel scaffolds are fluidic during application and annealed or crosslinked after application to the implant site in the subject. the microgel scaffolds may contain various therapeutic agents, including antibiotics and analgesics, throughout the gel.

Inventor(s): Westbrook WEAVER, Stephanie DESHAYES, Samuel TIMKO

CPC Classification: A61L27/52 (METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed ; preserving, e.g. sterilising, food or foodstuffs ; preparations for medical, dental or toiletry purposes ))

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