PREPARATION OF SOLID CYCLODEXTRIN COMPLEXES FOR OPHTHALMIC ACTIVE PHARMACEUTICAL INGREDIENT DELIVERY

Abstract: the present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. the compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. the ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 �m.

Inventor(s): Thorsteinn Loftsson, Zoltán Fülöp

CPC Classification: A61K47/6951 (the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit)

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