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20250177540. Stable Compositions Pegylated Ca (AMGEN .)

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STABLE COMPOSITIONS OF PEGYLATED CARFILZOMIB COMPOUNDS

Abstract: the present invention provides stable pharmaceutical compositions of pegylated carfilzomib compounds, methods for preparing the compositions, and uses of the compositions for treating cancer, including hematologic malignancies such as multiple myeloma. the compositions can be stored in frozen form or lyophilized to dry solid form.

Inventor(s): Alona TERAN, William CALLAHAN, Qahera MUNAIM, Rahul KAUSHIK

CPC Classification: A61K47/60 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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