PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM

Abstract: disclosed herein are compositions comprising an nsaid such as meloxicam and/or rizatriptan in combination with a cyclodextrin and/or a carbonate or a bicarbonate. these compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of the nsaid for the treatment of pain such as migraine, arthritis, and other conditions. also disclosed herein are methods of treating pain, such as migraine, comprising administering meloxicam and rizatriptan to a human being suffering from pain, such as migraine. for migraine, these methods may be particularly useful when the meloxicam and rizatriptan are administered while the human being is suffering from an acute attack of migraine pain or migraine aura. in some embodiments, the combination of meloxicam and rizatriptan may be administered in a manner that results in a tof meloxicam of 3 hours or less.

Inventor(s): Herriot Tabuteau

CPC Classification: A61K47/02 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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