BROAD SPECTRUM INHIBITORS OF CYTOMEGALOVIRUS

Abstract: the present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of cytomegalovirus infection in humans. a new class of n-arylpyrimidamine (napa) small molecules is disclosed that inhibits an early stage of the cytomegalovirus infection step of host cells. also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of cytomegalovirus infection.

Inventor(s): Timothy J. Opperman, Domenico Tortorella, Steven M. Kwasny, Zachary D. Aron, Thomas Gardner

CPC Classification: A61K31/506 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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