20250177374. Bcl-xl Inhibitory Compounds Having (AbbVie .)
BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same
Abstract: the present disclosure concerns bcl-xl inhibitors having low cell permeability, antibody drug conjugates (adcs) comprising the inhibitors, synthons useful for synthesizing the adcs, compositions comprising the inhibitors or adcs, and various methods of using the inhibitors and adcs.
Inventor(s): Scott L. Ackler, Nathan B. Bennett, Erwin R. Boghaert, Steve C. Cullen, George Doherty, Robin R. Frey, Anthony R. Haight, Andrew S. Judd, Aaron R. Kunzer, Violeta L. Marin, Xiaoqiang Shen, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Xilu Wang, Dennie S. Welch, Michael D. Wendt
CPC Classification: A61K31/4709 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))
Search for rejections for patent application number 20250177374
- Patent Applications
- AbbVie Inc.
- CPC A61K31/4709
- Scott L. Ackler of Gurnee IL US
- Nathan B. Bennett of Gurnee IL US
- Erwin R. Boghaert of Pleasant Prairie WI US
- Steve C. Cullen of Lake Villa IL US
- George Doherty of Libertyville IL US
- Robin R. Frey of Libertyville IL US
- Anthony R. Haight of Wadsworth IL US
- Andrew S. Judd of Grayslake IL US
- Aaron R. Kunzer of Arlington Heights IL US
- Violeta L. Marin of Chicago IL US
- Xiaoqiang Shen of Lincolnshire IL US
- Xiaohong Song of Grayslake IL US
- Andrew J. Souers of Libertyville IL US
- Gerard M. Sullivan of Lake Villa IL US
- Zhi-Fu Tao of Vernon Hills IL US
- Xilu Wang of Libertyville IL US
- Dennie S. Welch of Gurnee IL US
- Michael D. Wendt of Vernon Hills IL US