BMX MOUSE MODELS FOR BECKER MUSCULAR DYSTROPHY (BMD) V

Abstract: the invention described herein provides a mouse model of bmd (bmx). and uses thereof. the bmx mice of the invention recapitulate several features of bmd and harbour a phenotype intermediate to healthy and dmd null mdx52 mice. these bmx mice show deficits in muscle and cardiac function, reduced dystrophin protein in skeletal and cardiac muscle, and histopathology consistent with moderate dystrophy.

Inventor(s): Alyson Fiorillo, Christopher Heier

CPC Classification: A01K67/0276 (New or modified breeds of vertebrates)

Search for rejections for patent application number 20250176510