20250171622. Bis-octahydrop (Regeneron Pharmaceuticals, .)
BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDE DERIVATIVES AND PROTEIN CONJUGATES THEREOF FOR USE AS LXR AGONISTS
Abstract: provided herein are compounds or payloads, linker-payloads, antibody-drug conjugates, and compositions, and methods for the treatment of diseases and disorders associated with the liver x receptor, including bis-octahydrophenanthrene carboxamides and protein (e.g., antibody) drug conjugates thereof.
Inventor(s): Jesper GROMADA, Viktoria GUSAROVA, Amy HAN, Sokol HAXHINASTO, Andrew J. MURPHY, William OLSON, Matthew SLEEMAN
CPC Classification: C08L5/16 (COMPOSITIONS OF MACROMOLECULAR COMPOUNDS (compositions based on polymerisable monomers , ; artificial filaments or fibres ; textile treating compositions ))
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Categories:
- Patent Applications
- Regeneron Pharmaceuticals, Inc.
- CPC C08L5/16
- Jesper GROMADA of Concord MA US
- Viktoria GUSAROVA of Pleasantville NY US
- Amy HAN of Hockessin DE US
- Sokol HAXHINASTO of Brookfield CT US
- Andrew J. MURPHY of Croton-on-Hudson NY US
- William OLSON of Yorktown Heights NY US
- Matthew SLEEMAN of Yorktown Heights NY US