CAMELID ANTI-SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS ANTIBODIES

Abstract: anti-sars-cov-specific llama single domain antibodies, methods of making and characterizing those antibodies, and methods of using those antibodies are described herein. in some embodiments, the antibodies may bind to both sars-cov-1 and sars-cov-2. in some embodiments, the antibodies bind to sof the spike protein of sars-cov-2 including, for example, to the receptor binding domain (rbd) of s. in some embodiments, the antibodies may block the binding of sars-cov-1 and/or sars-cov-2 to ace-2.

Inventor(s): Ernesto R. Resnik, Anna Agnieszka Bajer, Cyrus B. Munshi, Kerri Ann Bostrom, Jody Bonnevier, Christine Andrea Goetz

CPC Classification: C07K16/1003 (PEPTIDES (peptides in foodstuffs ; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs ; preparations for medicinal purposes ; peptides containing beta-lactam rings ; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, ; ergot alkaloids of the cyclic peptide type ; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids ; macromolecular products derived from proteins ; preparation of glue or gelatine ; single cell proteins, enzymes ; genetic engineering processes for obtaining peptides ; compositions for measuring or testing processes involving enzymes ; investigation or analysis of biological material ))

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