PEPTIDE-MHC COMPACTS

Abstract: disclosed herein are antigenic peptide-mhc molecules, termed compacts, and methods of producing such molecules. also disclosed herein are methods of producing libraries of compact polynucleotides and polypeptides, and their exemplary use in capturing cancer neoepitope-reactive t cells.

Inventor(s): Olivier Dalmas, Zheng Pan, Michael Bethune, Songming Peng

CPC Classification: C07K14/70539 (PEPTIDES (peptides in foodstuffs ; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs ; preparations for medicinal purposes ; peptides containing beta-lactam rings ; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, ; ergot alkaloids of the cyclic peptide type ; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids ; macromolecular products derived from proteins ; preparation of glue or gelatine ; single cell proteins, enzymes ; genetic engineering processes for obtaining peptides ; compositions for measuring or testing processes involving enzymes ; investigation or analysis of biological material ))

Search for rejections for patent application number 20250171519