20250171419. Novel Nicotina (Heidelberg Pharma Research)
NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF
Abstract: the present disclosure pertains to the provision of nampt inhibitors, a method of synthesizing the same as well as their use in antibody-drug-conjugates. the present disclosure further pertains to pharmaceutical compositions comprising the nampt inhibitors of the disclosure and their use in cancer treatment. in a further aspect, the present disclosure pertains to a method of treatment using the nampt inhibitors of the disclosure.
Inventor(s): Pablo Ruedas-Batuecas, Hendrik Gruss, Anik贸 P谩lfi, Sarah-Jane Neuberth, Torsten Hechler
CPC Classification: C07D401/14 (HETEROCYCLIC COMPOUNDS (macromolecular compounds ))
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