BIOMIMETIC VESICLES AND USES THEREOF

Abstract: the present disclosure relates to unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. the disclosed compositions are useful for treating a subject with a disease or condition, such as a cardiovascular disease. in a further aspect, the cardiovascular disease can be a vascular stenosis or restenosis. also described herein are methods of making and using the unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. this abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Inventor(s): K. Craig Kent, Shaoqin Gong, Lianwang Guo, Bowen Wang, Guojun Chen, Go Urabe

CPC Classification: A61K47/6937 (the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit)

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