MODIFIED INVARIANT NATURAL KILLER T CELLS EXPRESSING A CHIMERIC ANTIGEN RECEPTOR AND USES THEREOF

Abstract: the present disclosure relates to modified invariant natural killer t (inkt) cells or type i natural killer t (nkt) cells (e.g., cd3itcr v�24-j�18 or cd3v�24) to express a cd7 chimeric antigen receptor (car) as therapeutic agents for the treatment of a cd7 cancer, and pharmaceutical compositions, methods of preparation, and therapeutic uses thereof.

Inventor(s): Xianzheng Zhou, Xin Huang

CPC Classification: A61K40/15 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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