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20250170136. 1,2,4-triazin-3(2h)-o (BAYER AKTIENGESELLSCHAFT)

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1,2,4-TRIAZIN-3(2H)-ONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES

Abstract: the present invention includes name compounds of general formula (i): (i) in which r, r, rand rare as defined herein, methods for their preparation, pharmaceutical compositions and combinations comprising said compounds, and their use for the treatment of hyperproliferative diseases.

Inventor(s): Stefan Nikolaus Gradl, Manuel Ellermann, Philip Lienau, Charlotte Christine Kopitz, Martin Lange, Adrian Tersteegen, Detlev Sülzle, Timothy A. Lewis, Heidi Greulich, Xiaoyun Wu

CPC Classification: A61K31/53 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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