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20250170133. Pharmaceutical Combina (Merck Sharp & Dohme LLC)

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PHARMACEUTICAL COMBINATIONS AND METHODS OF USE OF AMINO-PYRROLOPYRIMIDINONE COMPOUND

Abstract: the application relates to a pharmaceutical combination or combinational therapy comprising a therapeutically effective amount of the compound of formula (i), or a pharmaceutically acceptable salt thereof, and at least one second agent, or a pharmaceutically acceptable salt thereof, for use in the treatment of a btk-mediated disease or disorder.

Inventor(s): Mohammed Z.H. Farooqui, Patricia Marinello, Anson Kunjachan Abraham, Sudharshan Eathiraj, Brian E. Schwartz, Yi Yu, John C. Byrd, Elizabeth M. Muhowski, Jennifer A. Woyach

CPC Classification: A61K31/519 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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