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20250170114. Methods Tr (Praxis Precision Medicines, .)

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METHODS OF TREATMENT USING T-TYPE CALCIUM CHANNEL MODULATORS

Abstract: described herein, in part, are methods useful for treating a disease or condition relating to aberrant function or activity of a t-type calcium channel, such as essential tremor, in a subject in need thereof, comprising administering a t-type calcium channel inhibitor in combination with at least one of propranolol, primidone, topiramate, or a pharmaceutically acceptable salt thereof. also disclosed herein are compositions comprising the t-type calcium channel inhibitor and at least one of propranolol, primidone, topiramate, or a pharmaceutically acceptable salt thereof.

Inventor(s): Bernard Ravina

CPC Classification: A61K31/445 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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