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20250169739. Re (The Regents of the University of California)

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RECONSTRUCTION OF BRAIN ELECTRICAL ACTIVITY USING SPATIALLY RESOLVED ELECTROENCEPHALOGRAPHY

Abstract: methods, systems, and devices are described for reconstructing spatially resolved electrical activity in the brain. in some example embodiments, eeg and mri data are used to estimate volumetric distribution of electrostatic potential inside the mri domain throughout the entire brain. spatially and temporally varying field estimates can be generated using a brain wave model which is based on weakly evanescent transverse cortical wave propagation and constrained using the tissue properties gained from the mri data. the disclosed techniques enable brain activity imaging with high spatial and temporal resolution, thereby providing a tool for assessing functional brain states and monitoring changes in those states in relation to various normal and pathological conditions.

Inventor(s): Lawrence Robert Frank, Vitaly Ludwig Galinsky

CPC Classification: A61B5/372 (DIAGNOSIS; SURGERY; IDENTIFICATION (analysing biological material , e.g. ; obtaining records using waves other than optical waves, in general ))

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