SYSTEMS AND METHODS FOR IDENTIFYING PEPTIDES

Abstract: systems and methods for identifying a peptide for a query spectrum. the methods can involve receiving one or more parameters of a query spectrum; generating one or more candidate peptide sequences based on the one or more parameters of the query spectrum; generating a plurality of samples of the query spectrum; selecting at least one sample from the plurality of samples for comparison with the one or more candidate peptide sequences; determining a likelihood indicator for each of the one or more candidate peptide sequences based on a comparison with the at least one sample; applying a signal to noise filter to the one or more candidate peptide sequences based on the likelihood indicators for the candidate peptide sequences; and selecting at least one candidate peptide sequence as a proposed peptide sequence for the query spectrum based on the filtered candidate peptide sequences.

Inventor(s): John G. MARSHALL, Peter BOWDEN, Jaimie DUFRESNE

CPC Classification: G16B30/20 (BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY)

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