Methods and Compositions For Measuring Serum Analyte Levels From Biological Matrices

Abstract: provided herein are novel methods and compositions for determining serum analyte levels from biological matrices. the methods disclosed herein include determining a level of a protein in a serum of a patient in need thereof, comprising: (a) perturbing a soft tissue in a mouth of the patient: (b) collecting a sample of fluid from the oral, nasal, or other cavity of the patient; and (c) measuring the level of the protein in the sample of fluid from the cavity of the patient, wherein measuring the level of one or more protein in the sample of fluid from the sample of the patient affords a normalization or calibration curve allowing an accurate measurement of the level(s) of the desired analyte(s) in the serum of the patient.

Inventor(s): Bradley T. Messmer, Lesley Page

CPC Classification: G01N33/54388 ({based on lateral flow})

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