METHODS FOR PRESERVING HEALTHY INTESTINAL MICROBIOME DURING GROWTH PROMOTER ADMINSTRATION

Abstract: the present invention relates to methods of treating animals with an antimicrobial growth promoter (agp) to promote a healthy microbiome, the method comprising: a) providing test organisms and a control organism, b) administering a regular regimen of a different agp to each test organism for about two months, c) collecting dna from the intestinal content of the test organisms and of the control organism, d) sequencing the dna of the intestinal contents of the organisms to obtain taxonomic and functional profiles, thereby defining core intestinal microbiomes of the test and control organisms, e) comparing the core intestinal microbiomes of the test organisms and of the control organism, thereby determining which test organism has a healthy microbiome thereby determining which agp provides the most healthy microbiome, and f) treating the domesticated organism with the agp which provides the healthy microbiome.

Inventor(s): German PLATA, Troy B. HAWKINS, Arvind KUMAR

CPC Classification: C12Q1/689 (involving nucleic acids)

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