SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED GENE MANIPULATION AND USES THEREOF

Abstract: a system, a method, and a composition for targeted gene manipulation and use thereof are provided. the system specifically targets an rna molecule encoding an apoe4 protein, which may be used to treat diseases such as alzheimer's disease.

Inventor(s): Junbin LIANG, Shimin WANG, Hui XU, Huabao LIAO, Piao ZHANG, Xin LI, Desheng HUANGFU

CPC Classification: C12N15/902 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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