METHOD FOR PRODUCING PROLIFERATED HAIR FOLLICLE MESENCHYMAL CELLS, AND USE THEREOF

Abstract: provided are a method of producing hair follicle mesenchymal cells whose number has been expanded and whose hair regeneration abilities have been recovered, and a use thereof. the method of producing expanded hair follicle mesenchymal cells includes a main step of culturing hair follicle mesenchymal cells adhered to a substrate surface from a confluent state without passaging the cells. the main step includes culturing the hair follicle mesenchymal cells to make the cells proliferate further from the confluent state until the proliferated hair follicle mesenchymal cells are stacked to form cell layers including two or more stacked layers in at least part of the substrate surface.

Inventor(s): Junji FUKUDA, Tatsuto KAGEYAMA, Lei YAN

CPC Classification: C12N5/0666 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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