BISPECIFIC ANTIBODIES AGAINST CD277 AND A TUMOR-ANTIGEN

Abstract: the present invention relates to bispecific antibodies binding to cd277 and to a human tumor-antigen. the present invention relates also to polynucleotides encoding such bispecific antibodies and to vectors and host cells comprising such polynucleotides. in addition, the present invention relates to methods for producing such antibodies and to methods of using such antibodies in the treatment of diseases and their therapeutic use.

Inventor(s): Christoph Baumann, Klaus-Peter Kuenkele, Hans-Heinrich Oberg, Matthias Peipp, Daniela Wesch, Sandeep Kumar, Tadas Panavas, Nicolas Sabarth

CPC Classification: C07K16/2827 (PEPTIDES (peptides in foodstuffs ; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs ; preparations for medicinal purposes ; peptides containing beta-lactam rings ; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, ; ergot alkaloids of the cyclic peptide type ; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids ; macromolecular products derived from proteins ; preparation of glue or gelatine ; single cell proteins, enzymes ; genetic engineering processes for obtaining peptides ; compositions for measuring or testing processes involving enzymes ; investigation or analysis of biological material ))

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