2' AND/OR 5' AMINO-ACID ESTER PHOSPHORAMIDATE 3'-DEOXY ADENOSINE DERIVATIVES AS ANTI-CANCER COMPOUNDS

Abstract: the present invention relates to chemical compounds, the compounds for use in a method of treatment, particularly in a method of prophylaxis or treatment for cancer, a process for preparation of the compounds and pharmaceutical compositions comprising the compounds. the compounds may, in particular, be useful in the treatment of leukaemia, lymphoma and/or solid tumours in . the compounds are derivatives of cordycepin (3′-deoxyadenosine).

Inventor(s): Hugh Griffith, Christopher McGuigan, Valentina Ferrari, Michaela Serpi, Carmen Jimenez Antunez

CPC Classification: C07H19/20 (with the saccharide radical esterified by phosphoric or polyphosphoric acids)

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