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20250163068. Compounds (Praxis Precision Medicines, .)

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COMPOUNDS AND THEIR METHODS OF USE

Abstract: the present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. methods of treating a disease or condition relating to aberrant function of a sodium ion channel including dravet syndrome or epilepsy are also provided herein.

Inventor(s): Kiran Reddy, Gabriel Martinez Botella, Andrew Mark Griffin, Brian Edward Marron

CPC Classification: C07D487/04 (Ortho-condensed systems)

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