CHIMERIC NEUROTROPIC AAV CAPSIDS

Abstract: the invention relates to modified chimeric aav capsids, virus vectors comprising the same, and methods of using the vectors such as to target the nervous system. the invention further relates to modified chimeric aav capsids with improved infectivity to neural cells, virus vectors comprising the same, and methods of using the vectors to target neural cells with improved infectivity.

Inventor(s): Bin Xiao, Xiao Xiao, Juan Li

CPC Classification: A61K48/0041 (Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy)

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