ANTIBODY-DRUG CONJUGATES COMPRISING GLP1 PEPTIDOMIMETICS AND USES THEREOF

Abstract: described herein are protein-drug conjugates and compositions thereof that are useful, for example, for targeting glucagon-like peptide 1 receptor (glp1r). in certain embodiments, provided are peptidomimetic payloads and linker-payloads and methods of making same. more specifically, glp1 peptidomimetics, antibody-drug conjugates, and compositions which comprise anti-glp1r antibodies and glp1 peptidomimetic payloads and methods of treating glp1r-associated conditions are provided.

Inventor(s): Amy HAN, Haruka OKAMOTO, William OLSON

CPC Classification: A61K47/6849 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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