20250161460. Molecular Degraders Extrace (Yale University)
MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS
Abstract: the disclosure describes compounds of formula ia, which in non-limiting aspects contain an asialoglycoprotein receptor (asgpr) binding moiety and an anti-�ar binding moiety. compounds of formula ia are useful in preventing, treating, and/or ameliorating heart failure in a subject when administered in therapeutically effective amounts.
Inventor(s): David CAIANIELLO, Edward DERAMON, David SPIEGEL
CPC Classification: A61K47/549 ({Sugars, nucleosides, nucleotides or nucleic acids})
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