PEPTIDE CONJUGATE VACCINE COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

Abstract: the invention provides compositions and methods for the treatment of diseases associated with amyloid deposits of a� in the brain of a patient, such as alzheimer's disease. such methods entail administering a pharmaceutical composition comprising an immunogenic fragment of a� capable of inducing a beneficial immune response in the form of antibodies to a�. the immunogenic fragments comprise linear or multivalent peptides of a�. pharmaceutical compositions comprise the immunogenic fragment chemically linked to a carrier molecule which may be administered with an adjuvant.

Inventor(s): Yen-Pang Hsu, Sampat L. Ingale, Izzat T. Raheem, Jeffrey William Schubert, Ryan P. Staupe, Chengwei Wu

CPC Classification: A61K39/0007 (Medicinal preparations containing antigens or antibodies (materials for immunoassay ))

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