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20250161314. Method Treatment O (CATHAY GENERAL HOSPITAL)

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METHOD FOR TREATMENT OR IMPROVEMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE AND OBESITY BY LUMICHROME

Abstract: the present invention provides a method for a treatment or improvement of non-alcoholic fatty liver disease (nafld), comprising administering a composite to a subject in need thereof, wherein the composite comprises lumichrome. lumichrome can improve fatty liver and weight gains resulting from a high-fat diet, and improve the liver function index of aspartate transaminase, alanine transaminase or lactate dehydrogenase. further, lumichrome can also inhibit the increase of visceral fat and lipid droplets accumulation in the liver, and inhibit the mrna expression increase of acta2, cd36 or fabp1. therefore, lumichrome is effective for the treatment or improvement of non-alcoholic fatty liver disease and/or obesity.

Inventor(s): TING-LIN YEN

CPC Classification: A61K31/525 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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