20250161285. Bacterial Biofilm (THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL)

BACTERIAL BIOFILM INHIBITORS

Abstract: compounds according to formula i: wherein ar is an aryl or heteroaryl group, a is a c-calkyl, z and y are independently c-calkylene, x is c-calkylene, and r-rare selected from —h, halogen, c-calkyl, or phenyl, or a pharmaceutically acceptable salt thereof, are described. the compounds can be used to decrease the amount of biofilm in a subject, and can be used together with antibacterial agents for the treatment of bacterial infection.

Inventor(s): John S. GUNN, Jenna SANDALA, Christian Corey MELANDER, Katherine June WOOLARD

CPC Classification: A61K31/4535 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

Search for rejections for patent application number 20250161285